Highlights of Sunday's National Football League games

Eagles 21, Vikings 10

The Philadelphia Eagles used a ball-hawking defense and a back-breaking kickoff return to upset the Minnesota Vikings 21-10 on Sunday, handing the NFL's final undefeated team its first defeat.

Neither team's offense was effective and both team's quarterbacks struggled.

Philadelphia rookie Carson Wentz completed 16 of 28 passes for 138 yards.

Minnesota's Sam Bradford, who was traded from the Eagles before the season opener, was even worse for most of the game. He completed 24 of 41 passes for 224 yards.

Dolphins 28, Bills 25

Jay Ajayi became the fourth player in NFL history to rush for more than 200 yards in consecutive games, leading the Miami Dolphins to a 28-25 upset win over the Buffalo Bills.

Ajayi, a second-year running back from Boise State, ran 29 times for 214 yards and one touchdown as the Dolphins (3-4) ended Buffalo's four-game win streak.

Ajayi joined O.J. Simpson (1973 and 1976), Earl Campbell (1980) and Ricky Williams (2002) as the only players to have consecutive 200-yard games.

Lions 20 Redskins 17

Matthew Stafford connected with Anquan Boldin on an 18-yard touchdown pass with 16 seconds left, lifting the Detroit Lions to a 20-17 win over the Washington Redskins.

Stafford, making his 100th career start, engineered a six-play, 75-yard drive after Redskins quarterback Kirk Cousins scored on a 19-yard run with 1:05 remaining.

Stafford completed 18 of 29 passes for 266 yards as Detroit (4-3) won its third straight, all at home. The Redskins (4-3) had a four-game winning streak snapped.

Chiefs 27, Saints 21

Led by the efforts of running back Spencer Ware on offense and a defense that forced two turnovers, the Kansas City Chiefs beat the New Orleans Saints 27-21.

Ware touched the ball 19 times for 132 yards. He caught a short pass from quarterback Alex Smith and turned it into a 46-yard touchdown play in the first quarter.

The Kansas City (4-2) defense allowed New Orleans (2-4) quarterback Drew Brees to throw for 348 yards and three touchdowns.

Giants 17, Rams 10

Landon Collins and Dominique Rodgers-Cromartie each had two interceptions, fueling a strong defensive effort in the New York Giants' 17-10 win over the Los Angeles Rams at Twickenham Stadium in London.

The Giants (4-3) intercepted Rams quarterback Case Keenum four times. New York had only three takeaways all season before Sunday.

Jets 24, Ravens 16

Matt Forte generated 155 yards in total offense and scored two touchdowns as the New York Jets snapped a four-game losing streak with a 24-16 win over the Baltimore Ravens.

The Jets (2-5) lost starting quarterback Geno Smith in the second quarter but pulled away in the second half thanks to Forte, who had 103 total yards in the final two quarters. New York's opportunistic defense picked off Ravens quarterback Joe Flacco twice to set up a pair of scoring drives.

Bengals 31, Browns 17

Jeremy Hill rushed for a career-high 168 yards and Andy Dalton passed for 308 yards and two touchdowns, one of which was a 'Hail Mary' to A.J. Green at the end of the first half, to lift the Cincinnati Bengals to a 31-17 victory over the Cleveland Browns.

It was another rough afternoon for Cleveland (0-7), which lost quarterback Cody Kessler to a concussion in the second quarter. Kessler had just completed an 11-yard shovel pass when he was thrown hard to the turf by Bengals defensive end Carlos Dunlap.

Colts 34, Titans 26

The Indianapolis Colts might have saved their season with a 34-26 win over the Tennessee Titans.

A week after blowing a two-touchdown lead in the fourth quarter and losing in overtime, the Colts scored two touchdowns in an eight-second span.

Quarterback Andrew Luck hit Jack Doyle with a 7-yard touchdown pass with 1:55 left to give the Colts (3-4) a 27-23 lead, his third scoring strike of the day.

Raiders 33, Jaguars 16

The Oakland Raiders continued their sizzling road form with a 33-16 win over the Jacksonville Jaguars.

Oakland (5-2) is now 4-0 on the road this season. The last time it accomplished that came when the franchise advanced to the AFC Championship Game in 2000.