| 1 | David Villa
New York City FC | New York City FC | 33 | 24 |
| - | Nemanja Nikolic
Chicago Fire FC | Chicago Fire FC | 35 | 24 |
| 3 | Diego Valeri
Portland Timbers | Portland Timbers | 34 | 21 |
| 4 | Josef Martínez
Atlanta United FC | Atlanta United FC | 21 | 19 |
| - | Bradley Wright-Phillips
New York Red Bulls | New York Red Bulls | 35 | 19 |
| - | Ola Kamara
Columbus Crew SC | Columbus Crew SC | 39 | 19 |
| 7 | Ignacio Piatti
CF Montréal | CF Montréal | 28 | 17 |
| - | Sebastian Giovinco
Toronto FC | Toronto FC | 29 | 17 |
| - | Jozy Altidore
Toronto FC | Toronto FC | 31 | 17 |
| 10 | C.J. Sapong
Philadelphia Union | Philadelphia Union | 33 | 16 |
| 11 | Clint Dempsey
Seattle Sounders FC | Seattle Sounders FC | 33 | 15 |
| 12 | Daniel Royer
New York Red Bulls | New York Red Bulls | 29 | 14 |
| - | Erick Torres
Houston Dynamo FC | Houston Dynamo FC | 31 | 14 |
| - | David Accam
Chicago Fire FC | Chicago Fire FC | 31 | 14 |
| - | Christian Ramirez
Minnesota United FC | Minnesota United FC | 30 | 14 |
| - | Fredy Montero
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 36 | 14 |
| - | Justin Meram
Columbus Crew SC | Columbus Crew SC | 39 | 14 |
| 18 | Will Bruin
Seattle Sounders FC | Seattle Sounders FC | 36 | 13 |
| - | Romain Alessandrini
LA Galaxy | LA Galaxy | 30 | 13 |
| - | Héctor Villalba
Atlanta United FC | Atlanta United FC | 35 | 13 |
| - | Chris Wondolowski
San Jose Earthquakes | San Jose Earthquakes | 35 | 13 |
| 22 | Cyle Larin
Orlando City SC | Orlando City SC | 28 | 12 |
| - | Kei Kamara
New England Revolution | New England Revolution | 31 | 12 |
| - | Maximiliano Urruti
FC Dallas | FC Dallas | 32 | 12 |
| 25 | Alberth Elis
Houston Dynamo FC | Houston Dynamo FC | 30 | 11 |
| - | Roland Lamah
FC Dallas | FC Dallas | 32 | 11 |
| - | Mauro Manotas
Houston Dynamo FC | Houston Dynamo FC | 37 | 11 |
| - | Lee Nguyen
New England Revolution | New England Revolution | 31 | 11 |
| 29 | Fanendo Adi
Portland Timbers | Portland Timbers | 22 | 10 |
| - | Víctor Vázquez
Toronto FC | Toronto FC | 36 | 10 |
| - | Jack Harrison
New York City FC | New York City FC | 36 | 10 |
| 32 | Anthony Jackson-Hamel
CF Montréal | CF Montréal | 21 | 9 |
| - | Dom Dwyer
Orlando City SC | Orlando City SC | 12 | 9 |
| - | Miguel Almirón
Atlanta United FC | Atlanta United FC | 31 | 9 |
| - | Dominique Badji
Colorado Rapids | Colorado Rapids | 33 | 9 |
| - | Federico Higuaín
Columbus Crew SC | Columbus Crew SC | 31 | 9 |
| 37 | Abu Danladi
Minnesota United FC | Minnesota United FC | 27 | 8 |
| - | Gerso Fernandes
Sporting Kansas City | Sporting Kansas City | 33 | 8 |
| - | Sebastián Blanco
Portland Timbers | Portland Timbers | 34 | 8 |
| - | Justin Morrow
Toronto FC | Toronto FC | 33 | 8 |
| 41 | Roland Alberg
Philadelphia Union | Philadelphia Union | 24 | 7 |
| - | Gonzalo Verón
New York Red Bulls | New York Red Bulls | 27 | 7 |
| - | Tosaint Ricketts
Toronto FC | Toronto FC | 23 | 7 |
| - | Teal Bunbury
New England Revolution | New England Revolution | 28 | 7 |
| - | Yura Movsisyan
Real Salt Lake | Real Salt Lake | 28 | 7 |
| - | Romell Quioto
Houston Dynamo FC | Houston Dynamo FC | 26 | 7 |
| - | Juan Agudelo
New England Revolution | New England Revolution | 28 | 7 |
| - | Fafà Picault
Philadelphia Union | Philadelphia Union | 28 | 7 |
| - | Blerim Džemaili
CF Montréal | CF Montréal | 22 | 7 |
| - | Cristian Techera
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 32 | 7 |