At the 2014 World Indoor Championships in Sopot, Kilty clocked a personal best time of 6.49 seconds to claim 60m gold ahead of USA's Marvin Bracy and Qatar's Femi Ogunode.
This year's event takes place in Portland, Oregon starting on March 17 and the Brit is keen to emulate Canada's Bruny Surin by clinching a second world title.
The 26-year-old is also the current European Indoor 60m champion and although August's Olympics are weighing heavily on his mind, he is also set on making history indoors.
WADA to review cannabis rule after Richardson ban
"Bruny Surin won the world title twice. But I don't think anyone's gone back to back with the Europeans in the middle," Kilty told the Daily Record.
"At the minute I hold every major title over 60 metres. So to do it again would be massive.
"But I'm going to take each race step by step. The main thing this year is the Olympics. I want to break the 10-second barrier over 100m.
"If I qualify from the first two or three races we'll see what I can do at the World Indoors."
Burundi's Niyonsaba becomes first athlete with DSD to break world record in Zagreb
Great Britain set to be stripped of Olympic 4x100m relay silver after Ujah's 'B' sample positive