Leicester striker Vardy to miss Tottenham clash
The 31-year-old has a groin injury.
The striker will not be rushed back to action after missing the 1-1 draw at Fulham on Wednesday.
Jan Vertonghen is back in the Tottenham squad but fellow defenders Kieran Trippier and Juan Foyth are ruled out.
Vertonghen returns following a one-match ban but Trippier has a groin problem and Foyth a hamstring issue.
Mousa Dembele (ankle), Erik Lamela (thigh), Victor Wanyama (knee) and Davinson Sanchez (hamstring) are still sidelined.