Premier League preview: Can Chelsea edge ahead of Manchester United?

Injured (Brighton): Steve Sidwell.

Injured (Chelsea): None. Doubtful: David Luiz, Cesc Fabregas.

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Brighton have never beaten the defending top-flight champions in a league match.

Injured (Arsenal): Santi Cazorla, Olivier Giroud. Doubtful: Laurent Koscielny, Ainsley Maitland-Niles, Nacho Monreal, Mesut Ozil.

Injured (Crystal Palace): Mamadou Sakho, Scott Dann.

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Arsenal have never failed to score in 17 home league matches against Crystal Palace - they have 39 in total, averaging 2.3 per match.

Injured (Burnley): Chris Wood, Stephen Ward.

Injured (Man Utd): Zlatan Ibrahimovic, Eric Bailly, Michael Carrick.

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In 1996, United were 12 points behind Premier League leaders Newcastle United after 23 matches, but went on to lift the title. This season, United are currently 12 points behind Manchester City at the same stage.

Injured (Everton): Seamus Coleman, Ramiro Funes Mori, Leighton Baines, Michael Keane.

Injured (West Brom): Nacer Chadli. Doubtful: James Morrison.

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West Brom are the third-lowest scorers in the Premier League, with just 18 goals.

Injured (Leicester): Wes Morgan, Danny Simpson.

Injured (Watford): None. Doubtful: Tom Cleverley.

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Riyad Mahrez has scored in each of his last four Premier League matches against Watford.

Injured (Stoke): None. Doubtful: Ryan Shawcross, Glen Johnson.

Injured (Huddersfield): None.

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Huddersfield have won only two away matches in the Premier League this season - both by three goals.

Injured (West Ham): Winston Reid, Diafra Sakho, Michael Antonio, Edimilson Fernandes, Jose Fonte. Doubtful: Javier Hernandez, Cheikhou Kouyate.

Injured (Bournemouth): Joshua King, Junior Stanislas, Jermain Defoe, Tyrone Mings.

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This will be Eddie Howe's 100th Premier League game as a manager - the third-youngest English manager to reach the milestone, at the age of 40 years and 52 days.

Injured (Manchester City): Fabian Delph, Gabriel Jesus, Phil Foden, Benjamin Mendy.

Injured (Newcastle): Florian Lejeune, Jesus Gamez. Doubtful: Dwight Gayle, Chancel Mbemba, Aleksandar Mitrovic.

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City are unbeaten in 20 Premier League matches against Newcastle, winning 17 and drawing three - their longest unbeaten run against a side in their league history.

Injured (Southampton): Maya Yoshida, Charlie Austin.

Injured (Tottenham): Harry Winks, Danny Rose, Toby Alderweireld.

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Mauricio Pochettino is yet to lose a Premier League match at St Mary's since leaving Southampton at the end of 2013/14.