Ladbrokes Premiership champions in waiting Celtic have beaten their Glaswegian rivals three times already this season, but when the teams met at the same stage of the cup last year it was Rangers, then in the Championship, who came out on top.
The game finished in a 2-2 draw, with the Gers winning on penalties - a game that went a long way to ending Ronny Deila's time with the Hoops.
Celtic's Scott Sinclair with Rangers' Joey Barton after the game
Image credit: Reuters
It was Hibernian who went on win the competition, though, and the defending champions will face a Dons side who sit second in the Premiership table.
Hibs, the Championship pace-setters, are outsiders against the top three in the country but have pedigree, having appeared in the last four in each of the last three seasons.
Last year's success was their third Scottish Cup victory but first in 114 years.
The matches will take place at Hampden Park on April 22 and 23.