"Toulouse Football Club and Alain Casanova have decided on Thursday morning, by mutual consent, to end his contract as coach of the professional squad," TFC said in a statement.
Toulouse added that Denis Zanko, the technical director of the club's youth academy, would be in charge on a caretaking basis.
Toulouse, who have nine points from nine games, picked up two points from their last five matches.
Casanova, 58, had been in charge since 2018 after a first coaching stint at Toulouse from 2008-15.
(Reporting by Julien Pretot Editing by Robert Birsel)
Phillip Island (2015)