Victory sees Clermont move up to sixth, while Perpignan end the year in 10th place.
Toulouse will start 2011 as top dog in the Top 14 after a comfortable 25-8 win over SU Agen, thanks to a try from Vincent Clerc and some faultless kicking by David Skrela. All the leaders' points came in the first half and, despite a mini-revival after the break, it was too little too late for Agen.
Montpellier end the year in second after a hard-fought 22-16 home win over Biarritz while fourth-placed RacingMetro played out a dull 6-6 draw with Brive in Paris.
Stade Francais recorded a much-needed 26-16 win at Bourgoin while Iosefa Tekori scored a hat-trick in Castres' 25-10 victory over La Rochelle.
Rounding off the day's action, Toulon dropped to a 20-9 defeat to Aviron Bayonnais in a mid-table battle.