Williams’ preparations for his second session against Gilbert - who he beat 10-9 in the World Open final last August - were far from ideal with the Welshman heading for local hospital to get checked up for chest pains on Friday night trailing 5-3 that doctors assured him was not a heart problem.
He returned the following day and battled gamely to stay in contention, but trailed 9-7 ahead of Saturday’s concluding evening session after losing a tight final frame of the second session on the black as Gilbert made 69 to steal it by a point.
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Williams produced runs of 86 and 101 with Gilbert rolling in 82 and 100 as the highlight of the session.
The Welshman edged the first of the night to trail 9-8, but was forced to sit and suffer as Gilbert reeled off three quick frames with breaks of 62, 52 and an exquisite 139.
Williams produced 54 to stay alive, but Gilbert finished matters off with an 89 after Williams broke down on 33 in the 22nd frame to set up a meeting with Barry Hawkins or Kyren Wilson in the last eight.
Stephen Maguire ended James Cahill’s fairytale run at the World Championship with a 13-12 win over the qualifier in a tense last-16 clash.
But three-times winner Mark Selby crashed out losing 13-10 to world number 32 Gary Wilson in the last 16 as the Crucible Theatre threw up another shock.
Maguire dominated the final frame after 23-year-old amateur Cahill – who stunned tournament favourite Ronnie O’Sullivan 10-8 in the first round – had clawed his way back from 9-7 behind at the start of the afternoon session.
The Scotsman will face Ding Junhui or Judd Trump in the quarter-finals.

Cahill flukes black off four cushions after frame win

Cahill began the second session with as much fearlessness as he had displayed in ousting O’Sullivan as breaks of 69 and 52 saw him level matters at 9-9.
A 65 from Maguire saw him move 10-9 clear, but Cahill edged a tight 20th frame to head for the final mid-session interval at 10-10.
An outrageous fluke on the final red was the key to Cahill winning the 21st frame for an 11-10 lead before Maguire rolled in 72 to level up at 11-11.
Both men had several chances in the 23rd frame, but it was pinched by Maguire on the final brown after Cahill had been penalised for touching the pink while trying to pot a red on a break of 38.
Maguire recovered after Cahill jawed a straightish red, but then missed a frame ball pink. The drama was not over as Cahill blew the brown and with it his hopes of moving 12-11 ahead.

Cahill gets lucky on red after swerve shot

But the Blackpool player, who will start next season on the professional tour, would not collapse as he levelled again only for the experienced Scotsman, the 2004 UK champion, to produce an assured finish with the chances that came his way.
Cahill has the consolation of £30,000 for reaching the last 16 after coming through three qualifying rounds to reach this stage, and a return to the professional tour after two years in the doldrums.
World number two Selby dragged himself back into the match after resuming 9-7 behind this morning, but was helpless as Wilson won the final three frames to complete "the biggest win of his career".
Selby had picked up the first two frames of the day including a break of 81 to restore parity at 9-9 before the next two frames were split with a 66 from Selby again levelling at 10-10 heading for the mid-session interval.
Wallsend potter Wilson was dominant in the closing frame as knocks of 86 and a closing 92 consigned Selby to defeat.

‘Listen to the applause!’ – Gary Wilson shot delights crowd

Wilson’s reward is a quarter-final against two-times World Championship finalist Ali Carter or Zhou Yuelong meaning one qualifier is guaranteed to be playing in the semi-finals.
Selby joins world number one Ronnie O’Sullivan and former Masters holder Mark Allen on the Crucible casualty list, with defending champion Mark Williams also in trouble.

Second round latest scores (best of 25 frames)

  • Mark Williams (Wal) 9-13 David GIlbert (Eng)
  • Barry Hawkins (Eng) v Kyren Wilson (Eng)
  • John Higgins (Sco) 4-4 Stuart Bingham (Eng)
  • Shaun Murphy (Eng) 6-13 Neil Robertson (Aus)
  • Mark Selby (Eng) 10-13 Gary Wilson (Eng)
  • Ali Carter (Eng) v Zhou Yuelong (Chn)
  • Judd Trump (Eng) v Ding Junhui (Chn)
  • Stephen Maguire (Sco) 13-12 James Cahill (Eng)

First-round results & latest scores (best of 19 frames)

  • Mark Williams (Wal) 10-7 Martin Gould (Eng)
  • David Gilbert (Eng) 10-7 Joe Perry (Eng)
  • Barry Hawkins (Eng) 10-1 Li Hang (Chn)
  • Kyren Wilson (Eng) 10-4 Scott Donaldson (Sco)
  • John Higgins (Sco) 10-7 Mark Davis (Eng)
  • Stuart Bingham (Eng) 10-9 Graeme Dott (Sco)
  • Shaun Murphy (Eng) 10-0 Luo Honghao (Chn)
  • Neil Robertson (Aus) 10-1 Michael Georgiou (Cyp)
  • Mark Selby (Eng) 10-7 Zhao Xintong (Chn)
  • Luca Brecel (Bel) 9-10 Gary Wilson (Eng)
  • Jack Lisowski (Eng) 6-10 Ali Carter (Eng)
  • Mark Allen (NI) 7-10 Zhou Yeulong (Chn)
  • Judd Trump (Eng) 10-9 Thepchaiya Un-Nooh (Tha)
  • Ding Junhui (Chn) 10-7 Anthony McGill (Sco)
  • Stephen Maguire (Sco) 10-9 Tian Pengfei (Chn)
  • Ronnie O'Sullivan (Eng) 8-10 James Cahill (Eng)

Saturday, 27 April

  • Mark Williams (Wal) 7-9 David Gilbert (Eng)
  • Mark Selby (Eng) 10-13 Gary Wilson (Eng)
  • Stephen Maguire (Sco) 13-12 James Cahill (Eng)
  • John Higgins (Sco) 4-4 Stuart Bingham (Eng)
  • Mark Williams (Wal) v David Gilbert (Eng)
  • Judd Trump (Eng) v Ding Junhui (Chn)
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