British number one Dan Evans squandered four match points as he was knocked out of the Sardegna Open in Cagliari by Italian Lorenzo Musetti 6-1, 1-6, 7-6(8).
The world number 90 won the match in two hours and ten minutes after saving four match points in a breathless deciding tie-break.
Musetti will face either Laslo Djere or John Millman in the quarter finals.
Indian Wells order of play - Murray faces Zverev, Swiatek, Tsitsipas in action
- Opinion: Vaccine passports should be mandatory for players
- Auger Aliassime to link up with Toni Nadal
Musetti raced to a 6-1 opening set before Evans began to play extremely aggressively at the net, starting close to the service box when returning Musetti's serve.
It paid off as he stormed to a 6-1 set in 33 minutes and forced a decider which went to a dramatic tie-break.
Musetti went 3-6 and 7-8 down, but he fought back twice to seal his place in the quarter-finals on his second match point with a forehand drop shot winner.
"It was really tough. I was 3-6 down in the tie-break and he was playing good, always going to the net and always aggressive," Musetti said on-court afterwards.
"I tried to stay calm and tried to play each point. That is what I did and it worked, so I am really happy and really proud of myself with this win."
Rafael Nadal Top 5: Best shots from Spaniard at the 2021 Australian Open
Indian Wells order of play - Evans, Norrie, Medvedev, Andreescu in Monday's action
ATP Indian Wells
Evans battles back to see off Nishikori challenge