The 23-times Grand Slam singles champion lost 6-0 6-1 to Johanna Konta at the Mubadala Silicon Valley Classic last week, the heaviest defeat of her distinguished career.
The American icon, 36 and showing no signs of decline after losing in straight sets to Angelique Kerber in the Wimbledon final, had been given a wild card ahead of the US Open.
Australian Open
When is the Australian Open draw? Who could Djokovic face?
12/01/2022 AT 13:28
The 23-times Grand Slam singles winner, who gave birth last September, had not competed in Montreal since her run to the semi-finals in 2014 and last played the Rogers Cup in Toronto the following year.
She has moved up to 26 in the world rankings.
Australian Open
Australian Open 2022 - Who's playing, when's the draw, what's the schedule
10/01/2022 AT 14:15
Australian Open
Serena and Venus to miss Australian Open for first time since 1997
05/01/2022 AT 12:57