| 1 | Denis Bouanga
Los Angeles FC | Los Angeles FC | 36 | 25 |
| 2 | Cucho
Columbus Crew SC | Columbus Crew SC | 33 | 21 |
| 3 | Georgios Giakoumakis
Atlanta United FC | Atlanta United FC | 30 | 19 |
| - | Luciano Acosta
FC Cincinnati | FC Cincinnati | 36 | 19 |
| 5 | Brian White
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 34 | 16 |
| 6 | Dániel Gazdag
Philadelphia Union | Philadelphia Union | 35 | 15 |
| - | Hany Mukhtar
Nashville SC | Nashville SC | 36 | 15 |
| 8 | Alan Pulido
Sporting Kansas City | Sporting Kansas City | 32 | 14 |
| - | Julian Carranza
Philadelphia Union | Philadelphia Union | 33 | 14 |
| - | Facundo Torres
Orlando City SC | Orlando City SC | 33 | 14 |
| - | Christian Benteke
D.C. United | D.C. United | 31 | 14 |
| 12 | Duncan McGuire
Orlando City SC | Orlando City SC | 32 | 13 |
| - | Jordan Morris
Seattle Sounders FC | Seattle Sounders FC | 30 | 13 |
| - | Jesús Ferreira
FC Dallas | FC Dallas | 29 | 13 |
| - | Cristian Espinoza
San Jose Earthquakes | San Jose Earthquakes | 35 | 13 |
| 16 | Amine Bassi
Houston Dynamo FC | Houston Dynamo FC | 33 | 12 |
| - | Karol Swiderski
Charlotte FC | Charlotte FC | 32 | 12 |
| - | Thiago Almada
Atlanta United FC | Atlanta United FC | 33 | 12 |
| 19 | Sebastian Driussi
Austin FC | Austin FC | 28 | 11 |
| - | Carles Gil
New England Revolution | New England Revolution | 34 | 11 |
| - | Ryan Gauld
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 34 | 11 |
| 22 | Teemu Pukki
Minnesota United FC | Minnesota United FC | 14 | 10 |
| - | João Klauss
St. Louis CITY SC | St. Louis CITY SC | 21 | 10 |
| - | Lucas Zelarayán
Columbus Crew SC | Columbus Crew SC | 20 | 10 |
| - | Christian Ramirez
Columbus Crew SC | Columbus Crew SC | 35 | 10 |
| - | Nicholas Gioacchini
St. Louis CITY SC | St. Louis CITY SC | 34 | 10 |
| - | Mikael Uhre
Philadelphia Union | Philadelphia Union | 36 | 10 |
| - | Jeremy Ebobisse
San Jose Earthquakes | San Jose Earthquakes | 35 | 10 |
| 29 | Leonardo Campana
Inter Miami CF | Inter Miami CF | 26 | 9 |
| - | Evander
Portland Timbers | Portland Timbers | 27 | 9 |
| - | Carlos Vela
Los Angeles FC | Los Angeles FC | 39 | 9 |
| - | Corey Baird
Houston Dynamo FC | Houston Dynamo FC | 39 | 9 |
| - | Brandon Vazquez
FC Cincinnati | FC Cincinnati | 33 | 9 |
| - | Dániel Sallói
Sporting Kansas City | Sporting Kansas City | 38 | 9 |
| 35 | Samuel Adeniran
St. Louis CITY SC | St. Louis CITY SC | 20 | 8 |
| - | Gustavo Bou
New England Revolution | New England Revolution | 21 | 8 |
| - | Johnny Russell
Sporting Kansas City | Sporting Kansas City | 28 | 8 |
| - | Jefferson Savarino
Real Salt Lake | Real Salt Lake | 27 | 8 |
| - | Bongokuhle Hlongwane
Minnesota United FC | Minnesota United FC | 30 | 8 |
| 40 | Franck Boli
Portland Timbers | Portland Timbers | 29 | 7 |
| - | Diego Luna
Real Salt Lake | Real Salt Lake | 26 | 7 |
| - | Bobby Wood
New England Revolution | New England Revolution | 31 | 7 |
| - | Josef Martínez
Inter Miami CF | Inter Miami CF | 27 | 7 |
| - | Jáder Obrian
FC Dallas | FC Dallas | 32 | 7 |
| - | Tyler Boyd
LA Galaxy | LA Galaxy | 34 | 7 |
| - | Riqui Puig
LA Galaxy | LA Galaxy | 29 | 7 |
| - | Ryan Hollingshead
Los Angeles FC | Los Angeles FC | 37 | 7 |
| - | Albert Rusnák
Seattle Sounders FC | Seattle Sounders FC | 36 | 7 |
| - | Alvaro Barreal
FC Cincinnati | FC Cincinnati | 38 | 7 |
| 50 | Bernard Kamungo
FC Dallas | FC Dallas | 19 | 6 |